[Klaus]

I think that in terms of ergonomics it all depends on which system you were socialized.
I started with Canon and never really warmed up with Nikon for instance.
I think Panasonic is fairly related to Canon so I quite like that - less so Olympus.
Fuji is alright albeit a bit too traditional for my taste.
In the end, I consider all this a lesser concern because all of them are "good enough" and the ergonomics are secondary to other aspects.

e.g. the Oly M5 II is a killer when used with the 12-100 PRO.
The Fuji cameras are awesome with the Fuji prime lenses.
etc. pp.
As mentioned DSLRs are not my thing but I do understand their qualities and why they are popular among many users.